Principal Architect

About the Team

Enterprise Systems is the backbone of GSK’s internal operations in Digital & Tech, enabling GSK Global Functions teams such as Finance, Procurement, HR, Legal, Compliance, WREF, CGA and Corporate Secretariat to run seamlessly. This team designs and delivers cutting-edge digital platforms that power critical processes, ensuring efficiency, compliance, and scalability across the enterprise.

Enterprise Systems Management & Business Operations delivers digital solutions that support Enterprise Systems running as a high-performing organisation. This team drives financial discipline, operational rigour and strategic alignment across the ES portfolio that safeguard GSK’s integrity and reputation globally. By joining this team, you’ll help shape systems that support thousands of employees worldwide, driving innovation and reliability in the tools that keep GSK moving forward.

Job Purpose

Lead architecture for tactical, site-specific solutions where no global product or technology team is assigned across Global Supply Chain (GSC). Define target architectures, integration patterns and roadmaps for these solutions, acting as the architecture point of contact for the site. Connect site teams with relevant global domains including manufacturing, engineering, supply chain and quality. Partner with global functions, sites, product teams and suppliers to simplify and modernize the technology landscape, strengthen interoperability and resilience, and ensure alignment with GSC architecture and cybersecurity standards.

Key Responsibilities

• Providing architecture ownership for tactical, site-specific solutions where no global product or technology team is assigned, acting as the architecture point of contact for the site.

• Defining and governing integration patterns between site-specific systems, the Factory Integration Layer, Unified Namespace and enterprise data platforms.

• Developing and maintaining the Site Operations & Resilience domain architecture roadmap aligned with business priorities.

• Partnering with site system owners to define target-state capabilities and technology direction.

• Supporting site programmes involving site-specific systems and ensuring alignment with GSC architecture standards.

• Establishing domain standards, reference architectures and reusable integration patterns.

• Driving simplification, standardization and modernization of Site Operations & Resilience technology capabilities across GSC, including evaluating site technologies through assessments and proofs of concept, with cost estimates and technical debt considered in architecture recommendations.

• Conducting architecture reviews and providing practical guidance to project and product teams, applying threat modelling, resilience, observability and (Good Practice) GxP/engineering compliance requirements to site system designs and documenting supporting evidence.

• Collaborating with Enterprise Architecture, Smart Manufacturing, Data, Cloud and Cybersecurity teams on shared capabilities and platforms, and mentor junior architects and contribute to shared architecture patterns and the GSC architecture community of practice.

• Using approved AI tools to improve productivity and ways of working, applying sound judgement, validating outputs and following GSK Responsible AI, privacy and security requirements.

Basic Qualifications

• Bachelor’s degree in engineering, Computer Science, Information Systems, Automation Engineering, Industrial Engineering, or a related technical discipline.

• Minimum 8 years of experience in architecture, engineering systems, operational technology, industrial automation, or related disciplines.

• Experience in defining integration patterns across operational technology, industrial data, and enterprise platforms.

• Experience in supporting manufacturing site modernisation or technology programmes in a regulated environment.

• Experience in collaborating with site teams, technology teams, and external suppliers.

Preferred Qualification

• Master’s degree in enterprise architecture, Engineering Systems, Automation, Information Technology (IT), Technology Management, or a related discipline.

• The Open Group Architecture Framework (TOGAF) or an equivalent architecture certification.

• Experience in engineering, facilities, maintenance, and asset-management processes and systems.

• Experience in Industrial Internet of Things (IIoT), Operational Technology / Information Technology (OT/IT) integration, Factory Integration Layer, or Unified Namespace architectures.

• Experience in engineering compliance, industrial cybersecurity, and operational resilience.

• Experience in architecture governance, facilitation, and stakeholder management.

• Experience in translating complex technical topics into clear, accessible information for business, engineering, and site stakeholders.

AGTech

GSK-LI

Skills

Agile Methodology, API Management, CI/CD, Cloud Based Services, Computer Programming, Configuration Management (CM), Containerization, Database Management, High Availability (Inactive), Infrastructure As Code (IaC), Microservices Architecture, Network Security, Operating Systems (OS), System Monitors, Version Control System

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environ